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encephalitis - Herpes simplex

Advices

≥ 18 years
Priority Medication Remarks
Medication:

aciclovir iv 10mg/kg 3dd 14 to 21 days

General comments

Een behandelduur van 10 dagen aciclovir iv voor Herpes simplex encefalitis is uitgezocht in randomized controlled trials. Gezien er klinisch relapsen zijn beschreven na een behandelduur van 10 dagen is de expert based opinion om 14 - 21 dagen te behandelen. Stoppen kan eventueel op basis van de kliniek na 14 dagen. 

 

Sources

  1. Pubmed.gov publication # 18582201

    IDSA guideline: Tunkel AR, Glaser CA, Bloch KC, et al; Infectious Diseases Society of America. The management of encephalitis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2008;47:303-27. 

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-501674.2
Updated: 05/23/2023 - 16:37
Status: Published