ceftazidime/avibactam
      J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01D - Other Beta-Lactam Antibacterials -> J01DD - Third-Generation Cephalosporins -> J01DD52 - ceftazidime/avibactam
    
          
        Administration category:
         Limited
      
    
          
        Medicine group:
        antibacterial
      
    
          
        File parts:
                  ceftazidim
                  avibactam
              
    
          
        Brand name:
                  Zavicefta
              
      Standard dosages
| Weight | ROA | Load | Dosage | 
|---|---|---|---|
| ROA: iv | Load: - | Dosage: 2000/500mg 3 dd | 
Kidney function
| ROA | GFR | Dosage | Interval | Comments | 
|---|---|---|---|---|
| ROA: iv | ||||
| GFR: 30 - 50 | Dosage: 1000/250 mg | Interval: 8 Hours | ||
| GFR: 15 - 30 | Dosage: 750/187.5 mg | Interval: 12 Hours | ||
| GFR: 5 - 15 | Dosage: 750/187.5 mg | Interval: 24 Hours | ||
| GFR: <5 | Dosage: 750/187.5 mg | Interval: 48 Hours | ||
              
                Renal elimination: 
                97% wordt onveranderd met de urine uitgescheiden
              
            
                    
                              
        Renal function-replacement therapy
Hemo dialysis: 750 mg ceftazidim + 187.5 mg avibactam elke 48 uur; bij hemodialyse na de hemodialyse toedienen
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
          
            For individual advice, consult an expert on site.          
        
      Metadata
            Swab vid: M-439721.1
            Updated: 06/16/2019 - 20:05
            Status: Published
          
