atovaquon+proguanil
      P - Antiparasitic Products, Insecticides And Repellents -> P01 - Antiprotozoals -> P01B - Antimalarials -> P01BB - Biguanides -> P01BB51 - Proguanil, Combinations
    
          
        Administration category:
         Free
      
    
          
        Medicine group:
        antiparasitic
      
    
          
        File parts:
                  atovaquon
                  proguanil
              
    
          
        Brand name:
                  Malarone
              
      Standard dosages
| Weight | ROA | Load | Dosage | |
|---|---|---|---|---|
| ROA: po | Load: - | Dosage: 250/100mg 1 dd | ||
| Comments: profylaxe: 250/100 mg 1dd po. Therapie: zie bij malaria tropica | ||||
Kidney function
| ROA | GFR | Dosage | Interval | Comments | 
|---|---|---|---|---|
| ROA: po | ||||
| GFR: 30 - 50 | Dosage: proguanil: 100 mg/dag | |||
| GFR: 10 - 30 | Dosage: gecontraindiceerd | |||
| GFR: <10 | Dosage: gecontraindiceerd | |||
              
                Renal elimination: 
                0% (atavaquon), 30% (proguanil)
              
            
                    
                                
              
                Dosage: 
                dependent on kidney function
              
            
                    
        Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
          
            For individual advice, consult an expert on site.          
        
      Metadata
            Swab vid: M-2284.4
            Updated: 06/16/2019 - 20:05
            Status: Published
          
