lamivudine
J - Antiinfectives For Systemic Use -> J05 - Antivirals For Systemic Use -> J05A - Direct Acting Antivirals -> J05AF - Nucleoside And Nucleotide Reverse Transcriptase Inhibitors -> J05AF05 - Lamivudine
Administration category:
Free
Medicine group:
antiviral
Brand name:
Epivir
3TC
Safety margins
| Weight | ROA | Dosage |
|---|---|---|
|
ROA: po |
Dosage: min. 150mg 2 dd to max. 300mg 1 dd |
Kidney function
| ROA | GFR | Dosage | Interval | Comments |
|---|---|---|---|---|
| ROA: po | ||||
|
GFR: 50 - 80 |
Dosage: 150 mg 2 dd po |
|||
|
GFR: 30 - 50 |
Dosage: startdosis 150 mg, onderhoud 150 mg 1 dd po. |
|||
|
GFR: 15 - 30 |
Dosage: startdosis 150 mg, onderhoud 100 mg 1 dd po |
|||
|
GFR: 5 - 15 |
Dosage: startdosis 150 mg, onderhoud 50 mg 1 dd po. |
|||
|
GFR: <5 |
Dosage: startdosis 50 mg, onderhoud 25 mg 1 dd po. |
|||
Renal elimination:
70%
Renal function-replacement therapy
CAPD: startdosis 50-150 mg, vervolgens 25-50 mg 1x per dag, op geleide van de spiegel
Hemo dialysis: dialized - startdosis 50-150 mg, vervolgens 25-50 mg 1x per dag, op geleide van de spiegel
CAV / VVHD: startdosis 50-150 mg, vervolgens 25-50 mg 1x per dag, op geleide van de spiegel
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
For individual advice, consult an expert on site.
Metadata
Swab vid: M-1956.2
Updated: 06/16/2019 - 20:05
Status: Published