norfloxacine
      J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01M - Quinolone Antibacterials -> J01MA - Fluoroquinolones -> J01MA06 - Norfloxacin
    
          
        Administration category:
         Free
      
    
          
        Medicine group:
        antibacterial
      
    
    
          
        Brand name:
                  Noroxin
              
      Safety margins
| Weight | ROA | Dosage | 
|---|---|---|
| ROA: po | Dosage: min. 400mg 1 dd to max. 400mg 3 dd | 
Kidney function
| ROA | GFR | Dosage | Interval | Comments | 
|---|---|---|---|---|
| ROA: po | ||||
| GFR: 10 - 30 | Dosage: 400 mg | Interval: 24 Hours | ||
| GFR: 30 - 50 | Dosage: 400 mg | Interval: 12 Hours | ||
              
                Renal elimination: 
                25%
              
            
                    
                                
              
                Dosage: 
                dependent on kidney function
              
            
                    
        Renal function-replacement therapy
CAPD: Geef de normale keerdosis met een interval van 24 uur tussen 2 doses.
Hemo dialysis: Geef de normale keerdosis met een interval van 24 uur tussen 2 doses.
Interactions
| Interaction with (ATC): | Interaction with: | Expected effect: | 
|---|---|---|
| Interaction with (ATC): | Interaction with: aluminium- of magnesiumzouten bevattende antacida | Expected effect: vermindering absorptie norfloxacine | 
| Interaction with (ATC): | Interaction with: ijzerzouten | Expected effect: vermindering absorptie norfloxacine | 
| Interaction with (ATC): R03DA04 - Theophylline | Interaction with: | Expected effect: verhoging plasmaconcentratie theofylline | 
| Interaction with (ATC): A02BX02 - Sucralfate | Interaction with: | Expected effect: vermindering absorptie norfloxacine | 
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
          
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      Metadata
            Swab vid: M-1624.2
            Updated: 06/16/2019 - 20:05
            Status: Published
          
