isoniazide
J - Antiinfectives For Systemic Use -> J04 - Antimycobacterials -> J04A - Drugs For Treatment Of Tuberculosis -> J04AC - Hydrazides -> J04AC01 - Isoniazid
Administration category:
Free
Medicine group:
antibacterial
Safety margins
| Weight | ROA | Dosage |
|---|---|---|
|
ROA: po |
Dosage: min. 4mg/kg 1 dd to max. 8mg/kg 1 dd |
|
|
ROA: iv |
Dosage: min. 4mg/kg 1 dd to max. 8mg/kg 1 dd |
|
|
ROA: po |
Dosage: to max. 300mg 1 dd |
|
|
ROA: iv |
Dosage: to max. 300mg 1 dd |
Kidney function
Renal elimination:
5-10%
Dosage:
independent on kidney function
Interactions
| Interaction with (ATC): | Interaction with: | Expected effect: |
|---|---|---|
|
Interaction with (ATC): N03AF01 - Carbamazepine |
Interaction with: |
Expected effect: verhoging plasmaconcentratie carbamazepine |
|
Interaction with (ATC): N03AB02 - Phenytoin |
Interaction with: |
Expected effect: verhoging plasmaconcentratie fenytoïne |
|
Interaction with (ATC): |
Interaction with: aluminium bevattende antacida |
Expected effect: vermindering absorptie isoniazide |
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
For individual advice, consult an expert on site.
Metadata
Swab vid: M-1502.1
Updated: 06/16/2019 - 20:05
Status: Published