daptomycin
      J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01X - Other Antibacterials -> J01XX - Other Antibacterials -> J01XX09 - Daptomycin
    
          
        Administration category:
         Free
      
    
          
        Medicine group:
        antibacterial
      
    
    
          
        Brand name:
                  Cubicin
              
      Safety margins
| Weight | ROA | Dosage | |
|---|---|---|---|
| ROA: iv | Dosage: min. 4mg/kg 1 dd | ||
| Comments: Dosering afhankelijk van indicatie, in overleg met internist-infectioloog, arts-microbioloog of ziekenhuisapotheker | |||
Kidney function
| ROA | GFR | Dosage | Interval | Comments | 
|---|---|---|---|---|
| ROA: iv | ||||
| GFR: 50 - 80 | Dosage: 4 mg/kg | Interval: 24 Hours | ||
| GFR: 30 - 50 | Dosage: 4 mg/kg | Interval: 24 Hours | ||
| GFR: <30 | Dosage: 4 mg/kg | Interval: 48 Hours | ||
              
                Renal elimination: 
                50%
              
            
                    
                                
              
                Dosage: 
                dependent on kidney function
              
            
                    
        Renal function-replacement therapy
CAPD: Normale dosis elke 48 uur.
Hemo dialysis: Normale dosis elke 48 uur, op dialysedagen toedienen na dialyse.
CAV / VVHD: Normale dosis elke 48 uur.
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
          
            For individual advice, consult an expert on site.          
        
      Metadata
            Swab vid: M-1313.5
            Updated: 06/23/2023 - 15:28
            Status: Published
          
