cefamandol
      J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01D - Other Beta-Lactam Antibacterials -> J01DC - Second-Generation Cephalosporins -> J01DC03 - Cefamandole
    
          
        Administration category:
         Free
      
    
          
        Medicine group:
        antibacterial
      
    
    
          
        Brand name:
                  Mandol
              
      Safety margins
| Weight | ROA | Dosage | 
|---|---|---|
| ROA: iv | Dosage: min. 500mg 3 dd to max. 2000mg 4 dd | 
Kidney function
| ROA | GFR | Dosage | Interval | Comments | 
|---|---|---|---|---|
| ROA: iv | ||||
| GFR: 30 - 50 | Comments: 750 mg 3 dd - 1500 mg 4 dd iv | |||
| GFR: 10 - 30 | Comments: 500 mg 3 dd - 1000 mg 4 dd iv | |||
| GFR: <10 | Comments: 500 mg 2 dd iv | |||
Notes GFR general:
altijd wel oplaaddosis 1 g
            
              
                Renal elimination: 
                60-95%
              
            
                    
                                
              
                Dosage: 
                dependent on kidney function
              
            
                    
        Renal function-replacement therapy
CAPD: oplaaddosis 1 g, gevolgd door 500 mg elke 12 uur, vervolgens doseren op geleide van de spiegel
Hemo dialysis: oplaaddosis 1 g, gevolgd door 500 mg elke 12 uur, vervolgens doseren op geleide van de spiegel; op dialysedagen toedienen na de dialyse
CAV / VVHD: oplaaddosis 1 g, gevolgd door 500 mg elke 12 uur, vervolgens doseren op geleide van de spiegel
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
          
            For individual advice, consult an expert on site.          
        
      Metadata
            Swab vid: M-1112.3
            Updated: 11/10/2020 - 15:40
            Status: Published
          
