cefalotine
      J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01D - Other Beta-Lactam Antibacterials -> J01DB - First-Generation Cephalosporins -> J01DB03 - Cefalotin
    
          
        Administration category:
         Free
      
    
          
        Medicine group:
        antibacterial
      
    
    
          
        Brand name:
                  Keflin
              
      Safety margins
| Weight | ROA | Dosage | 
|---|---|---|
| ROA: iv | Dosage: min. 500mg 6 dd to max. 2000mg 6 dd | 
Kidney function
| ROA | GFR | Dosage | Interval | Comments | 
|---|---|---|---|---|
| ROA: iv | ||||
| GFR: 30 - 50 | Dosage: 1500 mg | Interval: 6 Hours | ||
| GFR: 10 - 30 | Dosage: 1000 mg | Interval: 6 Hours | ||
| GFR: 2 - 10 | Dosage: 500 mg | Interval: 6 Hours | ||
| GFR: <2 | Dosage: 500 mg | Interval: 8 Hours | ||
              
                Renal elimination: 
                70-80%
              
            
                    
                                
              
                Dosage: 
                dependent on kidney function
              
            
                    
        Renal function-replacement therapy
CAPD: 0.5 g elke 8-12 uur
Hemo dialysis: 0.5 g elke 8-12 uur.
CAV / VVHD: Continue venoveneuze hemodialyse/hemo(dia)filtratie: 1 g elke 6 uur.
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
          
            For individual advice, consult an expert on site.          
        
      Metadata
            Swab vid: M-1104.2
            Updated: 06/16/2019 - 20:05
            Status: Published
          
