cefalexine
      J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01D - Other Beta-Lactam Antibacterials -> J01DB - First-Generation Cephalosporins -> J01DB01 - Cefalexin
    
          
        Administration category:
         Free
      
    
          
        Medicine group:
        antibacterial
      
    
    
          
        Brand name:
                  Keforal
              
      Safety margins
| Weight | ROA | Dosage | 
|---|---|---|
| ROA: po | Dosage: min. 250mg 4 dd to max. 500mg 4 dd | |
| ROA: po | Dosage: to max. 4g/24h in 4 doses | 
Kidney function
| ROA | GFR | Dosage | Interval | Comments | 
|---|---|---|---|---|
| ROA: po | ||||
| GFR: 10 - 50 | Interval: 12 Hours | |||
| GFR: 5 - 10 | Interval: 24 Hours | |||
| GFR: <5 | Interval: 48 Hours | |||
              
                Renal elimination: 
                > 90%
              
            
                    
                                
              
                Dosage: 
                dependent on kidney function
              
            
                    
        Renal function-replacement therapy
CAPD: Normale keerdosis met een interval van 24 uur tussen 2 doses.
Hemo dialysis: Normale keerdosis met een interval van 24 uur tussen 2 doses, op dialysedagen toedienen na dialyse.
CAV / VVHD: Continue venoveneuze hemodialyse/hemo(dia)filtratie: normale keerdosis met een interval van 12 uur tussen 2 doses.
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
          
            For individual advice, consult an expert on site.          
        
      Metadata
            Swab vid: M-1093.2
            Updated: 06/16/2019 - 20:05
            Status: Published
          
